Endocrine Abstracts

Background: Isolated secondary hypothyroidism is rare. In the majority of cases the causes are genetic (gene mutations) or structural (mass effect or infiltration). Structural causes are usually associated with simultaneous deficiencies of other adenohypophyseal hormones. We present an identical twin with isolated secondary hypothyroidism.Case report: 1st Twin – 26-year-old obese lady, of Afro-carribean origin, presented with tiredness, weigh...

We present a case of 55 years old obese man with type 2 diabetes of 13 years duration, seen in diabetes clinic. His HbA1c had been 8–10% for about 7 years despite being on maximum doses of sulphonylurea and metformin.It was decided to start him on 30/70 mixed insulin and Metformin was continued. His HbA1c did not improve despite aggressive insulin titration. His injections became painful as insulin doses increased and resistance was noted on injecti...

A 36 year old gentleman presented to Accident and Emergency with 2 day history of generalised headache associated with dizziness. No significant previous medical history.Clinical examination: Alert, Oriented, Apyrexial, Pulse 80/mt regular, Blood pressure 132/70 with no postural drop. Systemic examination revealed no significant abnormality.Investigations and management: Full blood count, Glucose, Urea and Electrolytes, Liver funct...